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cacnb4.S calcium channel, voltage-dependent, beta 4 subunit S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108702958, updated on 4-Nov-2024

Summary

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Official Symbol
cacnb4.S
Official Full Name
calcium channel, voltage-dependent, beta 4 subunit S homeolog
Primary source
Xenbase:XB-GENE-17336342
Locus tag
XELAEV_18047093mg
See related
EnsemblRapid:ENSXLAG00005013436 AllianceGenome:Xenbase:XB-GENE-17336342
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable voltage-gated calcium channel activity. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be part of voltage-gated calcium channel complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; episodic ataxia; episodic ataxia type 5; and idiopathic generalized epilepsy 9. Orthologous to human CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cacnb4.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (60019906..60087651, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (53339240..53407215, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene nebulin S homeolog Neighboring gene ARF like GTPase 5A S homeolog Neighboring gene signal transducing adaptor molecule 2 S homeolog Neighboring gene formin like 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    60019906..60087651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018238781.2 → XP_018094270.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A8J0U3D6

  2. XM_018238782.2 → XP_018094271.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A1L8ENZ7, A0A974BU68
    Related
    ENSXLAP00005039725.1, ENSXLAT00005040644.1

  3. XM_018238783.2 → XP_018094272.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

    UniProtKB/TrEMBL
    A0A8J0TT16
    Related
    ENSXLAP00005039710.1, ENSXLAT00005040632.1
Nucleotide Protein Strain
Heading Accession and Version

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