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lsm6.L LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108699439, updated on 4-Nov-2024

Summary

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Official Symbol
lsm6.L
Official Full Name
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated L homeolog
Primary source
Xenbase:XB-GENE-17337464
Locus tag
XELAEV_18005517mg
See related
EnsemblRapid:ENSXLAG00005003551 AllianceGenome:Xenbase:XB-GENE-17337464
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable RNA binding activity. Acts upstream of or within midbrain development and neural precursor cell proliferation. Predicted to be located in P-body and nucleolus. Predicted to be part of sno(s)RNA-containing ribonucleoprotein complex; spliceosomal complex; and spliceosomal snRNP complex. Orthologous to human LSM6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lsm6.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (61769372..61774486, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (51345195..51350330, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 10 member 7 L homeolog Neighboring gene reelin domain-containing protein 1-like Neighboring gene zinc finger protein 827 L homeolog Neighboring gene uncharacterized LOC108699458

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An in vivo screen to identify candidate neurogenic genes in the developing Xenopus visual system. Bestman JE, et al. Dev Biol, 2015 Dec 15. PMID 25818835, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within maturation of SSU-rRNA IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within midbrain development IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
  
part_of Sm-like protein family complex IEA
Inferred from Electronic Annotation
more info
  
part_of U4/U6 x U5 tri-snRNP complex IEA
Inferred from Electronic Annotation
more info
  
part_of U6 snRNP IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of sno(s)RNA-containing ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
U6 snRNA-associated Sm-like protein LSm6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    61769372..61774486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018231526.2 → XP_018087015.1  U6 snRNA-associated Sm-like protein LSm6

    UniProtKB/TrEMBL
    A0A974DT88, Q66KU9
    Related
    ENSXLAP00005010587.1, ENSXLAT00005010754.1
    Conserved Domains (1) summary
    cd01726
    Location:7 → 74
    LSm6; Like-Sm protein 6
Nucleotide Protein Strain
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