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hspa1a.L heat shock protein family A (Hsp70) member 1A L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108696811, updated on 4-Nov-2024

Summary

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Official Symbol
hspa1a.L
Official Full Name
heat shock protein family A (Hsp70) member 1A L homeolog
Primary source
Xenbase:XB-GENE-17332950
See related
EnsemblRapid:ENSXLAG00005013574 AllianceGenome:Xenbase:XB-GENE-17332950
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
hsp72; hspa1; hsp70i; hspa1b; hsp70-1; hsp70-1a
Summary
Predicted to enable ATP binding activity and ATP-dependent protein folding chaperone. Predicted to be located in cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and vascular dementia. Orthologous to human HSPA1A (heat shock protein family A (Hsp70) member 1A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hspa1a.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (127710689..127730467, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (115750121..115769953, complement)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121395643 Neighboring gene cell wall protein IFF6-like Neighboring gene zinc finger protein 70 Neighboring gene potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heat shock cognate 71 kDa protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    127710689..127730467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018226469.2 → XP_018081958.1  heat shock cognate 71 kDa protein-like isoform X1

    UniProtKB/TrEMBL
    A0A8J0TDB8
    Related
    ENSXLAP00005040010.1, ENSXLAT00005040933.1

  2. XM_018226470.2 → XP_018081959.1  heat shock cognate 71 kDa protein-like isoform X2

    UniProtKB/TrEMBL
    A0A8J0TA12
    Conserved Domains (1) summary
    PTZ00009
    Location:1 → 612
    PTZ00009; heat shock 70 kDa protein; Provisional

  3. XM_041569684.1 → XP_041425618.1  heat shock cognate 71 kDa protein-like isoform X2

    UniProtKB/TrEMBL
    A0A8J0TA12
    Conserved Domains (1) summary
    PTZ00009
    Location:1 → 612
    PTZ00009; heat shock 70 kDa protein; Provisional
Nucleotide Protein Strain
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