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sorbs1.L sorbin and SH3 domain containing 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 108696213, updated on 4-Nov-2024

Summary

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Official Symbol
sorbs1.L
Official Full Name
sorbin and SH3 domain containing 1 L homeolog
Primary source
Xenbase:XB-GENE-17337462
Locus tag
XELAEV_18034804mg
See related
EnsemblRapid:ENSXLAG00005035821 AllianceGenome:Xenbase:XB-GENE-17337462
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
flaf2; r85fl; sh3d5; sorb1; sh3p12
Summary
Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sorbs1.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
36
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (36663926..36760771, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (34273606..34423438, complement)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene centromere protein T L homeolog Neighboring gene PDZ and LIM domain 1 L homeolog Neighboring gene annexin A7 L homeolog Neighboring gene protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
sorbin and SH3 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    36663926..36760771 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041568787.1 → XP_041424721.1  sorbin and SH3 domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8J1L593, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:984 → 1038
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1058 → 1115
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1524 → 1582
    SH3; Src Homology 3 domain superfamily

  2. XM_041568788.1 → XP_041424722.1  sorbin and SH3 domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8J1L589, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:983 → 1037
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1057 → 1114
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1523 → 1581
    SH3; Src Homology 3 domain superfamily

  3. XM_041568785.1 → XP_041424719.1  sorbin and SH3 domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1L6Z9, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:1040 → 1094
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1114 → 1171
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1580 → 1638
    SH3; Src Homology 3 domain superfamily

  4. XM_041568784.1 → XP_041424718.1  sorbin and SH3 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1L5A9
    Conserved Domains (4) summary
    cd11919
    Location:1519 → 1573
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1593 → 1650
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:671 → 714
    Sorb; Sorbin homologous domain
    cl17036
    Location:2059 → 2117
    SH3; Src Homology 3 domain superfamily

  5. XM_041568790.1 → XP_041424724.1  sorbin and SH3 domain-containing protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8J1L705, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:958 → 1012
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1032 → 1089
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1498 → 1556
    SH3; Src Homology 3 domain superfamily

  6. XM_041568786.1 → XP_041424720.1  sorbin and SH3 domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8J1L806, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:1039 → 1093
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1113 → 1170
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1579 → 1637
    SH3; Src Homology 3 domain superfamily

  7. XM_041568792.1 → XP_041424726.1  sorbin and SH3 domain-containing protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8J1L598
    Conserved Domains (4) summary
    cd11919
    Location:1039 → 1093
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1113 → 1170
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1218 → 1276
    SH3; Src Homology 3 domain superfamily

  8. XM_041568794.1 → XP_041424728.1  sorbin and SH3 domain-containing protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A8J1L5C2
    Related
    ENSXLAP00005107298.1, ENSXLAT00005109424.1
    Conserved Domains (4) summary
    cd11919
    Location:1019 → 1073
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1093 → 1150
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:652 → 695
    Sorb; Sorbin homologous domain
    cl17036
    Location:1218 → 1276
    SH3; Src Homology 3 domain superfamily

  9. XM_041568791.1 → XP_041424725.1  sorbin and SH3 domain-containing protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8J1L813
    Conserved Domains (4) summary
    cd11919
    Location:1039 → 1093
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1113 → 1170
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:672 → 715
    Sorb; Sorbin homologous domain
    cl17036
    Location:1238 → 1296
    SH3; Src Homology 3 domain superfamily

  10. XM_041568793.1 → XP_041424727.1  sorbin and SH3 domain-containing protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8J1L594, A0A974CFL7
    Conserved Domains (4) summary
    cd11919
    Location:778 → 832
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:852 → 909
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:411 → 454
    Sorb; Sorbin homologous domain
    cl17036
    Location:1274 → 1332
    SH3; Src Homology 3 domain superfamily

  11. XM_041568789.1 → XP_041424723.1  sorbin and SH3 domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8J1L5B7, A0A974BRM3
    Conserved Domains (4) summary
    cd11919
    Location:1019 → 1073
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:1093 → 1150
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:651 → 694
    Sorb; Sorbin homologous domain
    cl17036
    Location:1515 → 1573
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
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