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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Manis javanica (Malayan pangolin) ]

Gene ID: 108403360, updated on 14-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023435931.1 (5222307..5254035, complement)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016538167.1 (20202..99762)

NW_023435931.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118968908 Neighboring gene protein kinase C theta Neighboring gene uncharacterized LOC118968921 Neighboring gene 40S ribosomal protein S26-like Neighboring gene RNA binding motif protein 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023435931.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    5222307..5254035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037001433.1 → XP_036857328.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_037001397.1 → XP_036857292.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:129 → 315
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    cl17190
    Location:2 → 126
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  3. XM_037001409.1 → XP_036857304.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    Conserved Domains (2) summary
    pfam00300
    Location:129 → 315
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    cl17190
    Location:2 → 126
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  4. XM_037001423.1 → XP_036857318.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    Conserved Domains (2) summary
    pfam00300
    Location:129 → 315
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    cl17190
    Location:2 → 126
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  5. XM_037001431.1 → XP_036857326.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    Conserved Domains (2) summary
    pfam00300
    Location:129 → 315
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    cl17190
    Location:2 → 126
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  6. XM_037001418.1 → XP_036857313.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Conserved Domains (2) summary
    pfam00300
    Location:129 → 315
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    cl17190
    Location:2 → 126
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RNA

  1. XR_005056788.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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