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CHRNA1 cholinergic receptor nicotinic alpha 1 subunit [ Manis javanica (Malayan pangolin) ]

Gene ID: 108395367, updated on 14-Mar-2024

Summary

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Gene symbol
CHRNA1
Gene description
cholinergic receptor nicotinic alpha 1 subunit
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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See CHRNA1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436050.1 (1033892..1048644, complement)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016531789.1 (168027..184633, complement)

NW_023436050.1Genomic Context describing neighboring genes Neighboring gene integral membrane protein GPR155-like Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene uncharacterized LOC118972806 Neighboring gene chimerin 1 Neighboring gene iron-sulfur cluster assembly enzyme ISCU, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholine receptor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436050.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    1033892..1048644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017657562.2 → XP_017513051.1  acetylcholine receptor subunit alpha isoform X1

  2. XM_037020657.1 → XP_036876552.1  acetylcholine receptor subunit alpha isoform X2

    Conserved Domains (2) summary
    cd19014
    Location:40 → 249
    LGIC_ECD_nAChR_A1; extracellular domain of nicotinic acetylcholine receptor subunit alpha 1 (CHRNA1)
    cd19064
    Location:250 → 339
    LGIC_TM_nAChR; transmembrane domain of nicotinic acetylcholine receptor (nAChR)
Nucleotide Protein
Heading Accession and Version

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