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PLCB1 phospholipase C beta 1 [ Manis javanica (Malayan pangolin) ]

Gene ID: 108394257, updated on 14-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436019.1 (11620083..12302520)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016531007.1 (47217..585154)

NW_023436019.1Genomic Context describing neighboring genes Neighboring gene hydroxyacid oxidase 1 Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene uncharacterized LOC118972272 Neighboring gene phospholipase C beta 4 Neighboring gene lysosomal associated membrane protein family member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436019.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    11620083..12302520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037017496.1 → XP_036873391.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:841 → 943
    PRK12727; flagellar biosynthesis protein FlhF
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1172
    PLC-beta_C; PLC-beta C terminal

  2. XM_037017497.1 → XP_036873392.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:841 → 943
    PRK12727; flagellar biosynthesis protein FlhF
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  3. XM_037017498.1 → XP_036873393.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    Conserved Domains (6) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:740 → 842
    PRK12727; flagellar biosynthesis protein FlhF
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain

  4. XM_017655684.2 → XP_017511173.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    Conserved Domains (6) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:740 → 842
    PRK12727; flagellar biosynthesis protein FlhF
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain

  5. XM_037017499.1 → XP_036873394.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    Conserved Domains (6) summary
    cd00275
    Location:576 → 695
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:215 → 542
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PRK12727
    Location:740 → 842
    PRK12727; flagellar biosynthesis protein FlhF
    cd16208
    Location:52 → 202
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam08703
    Location:902 → 1071
    PLC-beta_C; PLC-beta C terminal
    cl17171
    Location:1 → 47
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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