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C2cd4b C2 calcium-dependent domain containing 4B [ Rattus norvegicus (Norway rat) ]

Gene ID: 108351734, updated on 17-Aug-2024

Summary

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Symbol
C2cd4bprovided by RGD
Full Name
C2 calcium-dependent domain containing 4Bprovided by RGD
Primary source
RGD:1591932
See related
EnsemblRapid:ENSRNOG00000065921 AllianceGenome:RGD:1591932
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nlf2; Fam148b
Summary
Predicted to be involved in positive regulation of acute inflammatory response; regulation of cell adhesion; and regulation of vascular permeability involved in acute inflammatory response. Orthologous to human C2CD4B (C2 calcium dependent domain containing 4B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human all
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Genomic context

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See C2cd4b in Genome Data Viewer
Location:
8q24
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (77254327..77277620)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (68372793..68396477)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (73555414..73580848)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 12, pseudogene 1 Neighboring gene uncharacterized LOC100911360 Neighboring gene large ribosomal subunit protein eL42-like Neighboring gene C2 calcium-dependent domain containing 4A Neighboring gene vacuolar protein sorting 13 homolog C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel gene family induced by acute inflammation in endothelial cells. Warton K, et al. Gene, 2004 Nov 10. PMID 15527968
  2. Characterization of the piRNA complex from rat testes. Lau NC, et al. Science, 2006 Jul 21. PMID 16778019
  3. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in positive regulation of acute inflammatory response ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of vascular permeability involved in acute inflammatory response ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
C2 calcium-dependent domain-containing protein 4B
Names
family with sequence similarity 148, member B
nuclear localized factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    77254327..77277620
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_576426.8 → XP_576426.2  C2 calcium-dependent domain-containing protein 4B

    See identical proteins and their annotated locations for XP_576426.2

    UniProtKB/TrEMBL
    A0A8I6A9N9
    Related
    ENSRNOP00000106491.1, ENSRNOT00000094584.2

  2. XM_063266343.1 → XP_063122413.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9

  3. XM_039082500.2 → XP_038938428.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9

  4. XM_039082501.2 → XP_038938429.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9

  5. XM_039082499.2 → XP_038938427.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9

  6. XM_063266342.1 → XP_063122412.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9

  7. XM_039082491.2 → XP_038938419.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9
    Related
    ENSRNOP00000110109.1, ENSRNOT00000145744.1

  8. XM_039082494.2 → XP_038938422.1  C2 calcium-dependent domain-containing protein 4B

    UniProtKB/TrEMBL
    A0A8I6A9N9
Nucleotide Protein Strain
Heading Accession and Version

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