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CBL Cbl proto-oncogene [ Cebus imitator (Panamanian white-faced capuchin) ]

Gene ID: 108300640, updated on 14-Mar-2024

Summary

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Gene symbol
CBL
Gene description
Cbl proto-oncogene
See related
Ensembl:ENSCCAG00000030401
Gene type
protein coding
RefSeq status
MODEL
Organism
Cebus imitator
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Cebus
Orthologs
human mouse all
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Genomic context

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See CBL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Cebus_imitator-1.0 (GCF_001604975.1) Unplaced Scaffold NW_016107343.1 (6987978..7095580)

NW_016107343.1Genomic Context describing neighboring genes Neighboring gene NHERF family PDZ scaffold protein 4 Neighboring gene dynein regulatory complex subunit 12 homolog Neighboring gene uncharacterized LOC119470335 Neighboring gene 60S ribosomal protein L7a-like Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene melanoma cell adhesion molecule Neighboring gene small nucleolar RNA ACA64 Neighboring gene 40S ribosomal protein S3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_016107343 Unplaced Scaffold Reference Cebus_imitator-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cebus imitator Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cebus_imitator-1.0

Genomic

  1. NW_016107343.1 Reference Cebus_imitator-1.0

    Range
    6987978..7095580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037736738.1 → XP_037592666.1  E3 ubiquitin-protein ligase CBL isoform X1

    UniProtKB/TrEMBL
    A0A2K5RB13
    Conserved Domains (6) summary
    cd09920
    Location:270 → 366
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    PHA03247
    Location:494 → 767
    PHA03247; large tegument protein UL36; Provisional
    cd14393
    Location:871 → 910
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:376 → 441
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:57 → 186
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:193 → 276
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  2. XM_017523530.2 → XP_017379019.1  E3 ubiquitin-protein ligase CBL isoform X2

    UniProtKB/TrEMBL
    A0A2K5RAX8, A0A2K5RB13
    Related
    ENSCCAP00000025290.1, ENSCCAT00000042812.1

  3. XM_017523531.2 → XP_017379020.1  E3 ubiquitin-protein ligase CBL isoform X3

    UniProtKB/TrEMBL
    A0A2K5RB13

RNA

  1. XR_005199226.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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