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LINC02253 long intergenic non-protein coding RNA 2253 [ Homo sapiens (human) ]

Gene ID: 107984764, updated on 10-Oct-2023

Summary

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Official Symbol
LINC02253provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 2253provided by HGNC
Primary source
HGNC:HGNC:53151
See related
Ensembl:ENSG00000259485 AllianceGenome:HGNC:53151
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
15q26.2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (97234292..97432090)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (94999395..95197348)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371004 Neighboring gene uncharacterized LOC105371005 Neighboring gene MPRA-validated peak2437 silencer Neighboring gene MPRA-validated peak2438 silencer Neighboring gene uncharacterized LOC105371006 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:97838555-97839198 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:97839199-97839840 Neighboring gene RNA, 7SL, cytoplasmic 677, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr15:97929831-97931030 Neighboring gene long intergenic non-protein coding RNA 2254 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr15:97961806-97962372 Neighboring gene RNA, 5S ribosomal pseudogene 401 Neighboring gene uncharacterized LOC101927310 Neighboring gene uncharacterized LOC105371007

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA LINC02253 activates KRT18/MAPK/ERK pathway by mediating N6-methyladenosine modification of KRT18 mRNA in gastric cancer. Gao Z, et al. Carcinogenesis, 2022 Jun 4. PMID 35136989

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LncRNA LINC02253 activates KRT18/MAPK/ERK pathway by mediating N6-methyladenosine modification of KRT18 mRNA in gastric cancer.
    Title: LncRNA LINC02253 activates KRT18/MAPK/ERK pathway by mediating N6-methyladenosine modification of KRT18 mRNA in gastric cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

Genotypes

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_183853.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC020704, AC109808
    Related
    ENST00000666169.1

  2. NR_183854.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC020704, AC109808
    Related
    ENST00000660428.1

  3. NR_183855.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC020704, AC109808

  4. NR_183856.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC020704, AC109808
    Related
    ENST00000655490.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    97234292..97432090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    94999395..95197348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases