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TPH1 tryptophan hydroxylase 1 [ Miniopterus natalensis ]

Gene ID: 107546725, updated on 30-Mar-2024

Summary

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Gene symbol
TPH1
Gene description
tryptophan hydroxylase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Miniopterus natalensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Miniopteridae; Miniopterus
Orthologs
human mouse all
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Genomic context

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See TPH1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current Mnat.v1 (GCF_001595765.1) Unplaced Scaffold NW_015504217.1 (55333..69194)

NW_015504217.1Genomic Context describing neighboring genes Neighboring gene serum amyloid A like 1 Neighboring gene E3 ubiquitin-protein ligase RBBP6 pseudogene Neighboring gene secretion regulating guanine nucleotide exchange factor Neighboring gene potassium voltage-gated channel subfamily C member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015504217.1 Unplaced Scaffold Reference Mnat.v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tryptophan 5-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aromatic amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in serotonin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: tryptophan 5-hydroxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Miniopterus natalensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnat.v1

Genomic

  1. NW_015504217.1 Reference Mnat.v1

    Range
    55333..69194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016225210.1 → XP_016080696.1  LOW QUALITY PROTEIN: tryptophan 5-hydroxylase 1

    Conserved Domains (3) summary
    TIGR01270
    Location:3 → 438
    Trp_5_monoox; tryptophan 5-monooxygenase, tetrameric
    pfam00351
    Location:106 → 434
    Biopterin_H; Biopterin-dependent aromatic amino acid hydroxylase
    cl09141
    Location:18 → 91
    ACT; ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme
Nucleotide Protein
Heading Accession and Version

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