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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107506600, updated on 30-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Locus tag
HJG63_015170
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416312.1 (34887797..34979209, complement)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015493365.1 (4644329..4735169)

NW_023416312.1Genomic Context describing neighboring genes Neighboring gene melanoma-associated antigen D2 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene trophinin Neighboring gene small nucleolar RNA SNORA11 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416312.1 Reference mRouAeg1.p

    Range
    34887797..34979209 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016137309.2 → XP_015992795.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A7J8ELD1, A0A7J8ELK1
    Conserved Domains (2) summary
    pfam00300
    Location:231 → 417
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:7 → 228
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_036226694.1 → XP_036082587.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A7J8ELD1, A0A7J8ELK1
    Conserved Domains (2) summary
    pfam00300
    Location:231 → 417
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:7 → 228
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_016137308.2 → XP_015992794.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A7J8ELK1
    Conserved Domains (3) summary
    pfam00300
    Location:254 → 406
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:44 → 198
    AAA_33; AAA domain

  4. XM_016137307.2 → XP_015992793.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A7J8EL70, A0A7J8ELK1
    Conserved Domains (2) summary
    pfam00300
    Location:254 → 440
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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