U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

APC2 APC regulator of WNT signaling pathway 2 [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107500934, updated on 30-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
APC2
Gene description
APC regulator of WNT signaling pathway 2
Locus tag
HJG63_000810
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See APC2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416291.1 (54243523..54262489, complement)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015495066.1 (98385..111927, complement)

NW_023416291.1Genomic Context describing neighboring genes Neighboring gene proprotein convertase subtilisin/kexin type 4 Neighboring gene chromosome unknown C19orf25 homolog Neighboring gene DAZ associated protein 1 Neighboring gene ribosomal protein S15

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables gamma-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of microtubule depolymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pattern specification process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
adenomatous polyposis coli protein 2
Names
APC2, WNT signaling pathway regulator

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416291.1 Reference mRouAeg1.p

    Range
    54243523..54262489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036234217.1 → XP_036090110.1  adenomatous polyposis coli protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A7J8BNQ7
    Conserved Domains (11) summary
    PHA03269
    Location:2122 → 2245
    PHA03269; envelope glycoprotein C; Provisional
    PHA03247
    Location:1330 → 1603
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:1514 → 1948
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    sd00043
    Location:546 → 579
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:30 → 81
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:634 → 673
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1258 → 1279
    APC_r; APC repeat
    pfam05956
    Location:1769 → 2079
    APC_basic; APC basic domain
    pfam11414
    Location:148 → 229
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:716 → 964
    Arm_APC_u3; Armadillo-associated region on APC
    pfam18797
    Location:381 → 450
    APC_rep; Adenomatous polyposis coli (APC) repeat

  2. XM_036234218.1 → XP_036090111.1  adenomatous polyposis coli protein 2 isoform X2

    Conserved Domains (11) summary
    PHA03269
    Location:2098 → 2221
    PHA03269; envelope glycoprotein C; Provisional
    PHA03247
    Location:1306 → 1579
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:1490 → 1924
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    sd00043
    Location:522 → 555
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:6 → 57
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:610 → 649
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1234 → 1255
    APC_r; APC repeat
    pfam05956
    Location:1745 → 2055
    APC_basic; APC basic domain
    pfam11414
    Location:124 → 205
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:692 → 940
    Arm_APC_u3; Armadillo-associated region on APC
    pfam18797
    Location:357 → 426
    APC_rep; Adenomatous polyposis coli (APC) repeat

  3. XM_036234219.1 → XP_036090112.1  adenomatous polyposis coli protein 2 isoform X2

    Conserved Domains (11) summary
    PHA03269
    Location:2098 → 2221
    PHA03269; envelope glycoprotein C; Provisional
    PHA03247
    Location:1306 → 1579
    PHA03247; large tegument protein UL36; Provisional
    PRK07764
    Location:1490 → 1924
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    sd00043
    Location:522 → 555
    ARM; armadillo repeat [structural motif]
    pfam16689
    Location:6 → 57
    APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
    pfam00514
    Location:610 → 649
    Arm; Armadillo/beta-catenin-like repeat
    pfam05923
    Location:1234 → 1255
    APC_r; APC repeat
    pfam05956
    Location:1745 → 2055
    APC_basic; APC basic domain
    pfam11414
    Location:124 → 205
    Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
    pfam16629
    Location:692 → 940
    Arm_APC_u3; Armadillo-associated region on APC
    pfam18797
    Location:357 → 426
    APC_rep; Adenomatous polyposis coli (APC) repeat
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.