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PLCG1 phospholipase C gamma 1 [ Protobothrops mucrosquamatus ]

Gene ID: 107287257, updated on 14-Mar-2024

Summary

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Gene symbol
PLCG1
Gene description
phospholipase C gamma 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Protobothrops mucrosquamatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Protobothrops
Orthologs
human mouse all
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Genomic context

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See PLCG1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
101 current P.Mucros_1.0 (GCF_001527695.2) Unplaced Scaffold NW_015386705.1 (709882..791038, complement)

NW_015386705.1Genomic Context describing neighboring genes Neighboring gene lipin 3 Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene DNA topoisomerase I

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015386705 Unplaced Scaffold Reference P.Mucros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Protobothrops mucrosquamatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.Mucros_1.0 Primary Assembly

Genomic

  1. NW_015386705.1 Reference P.Mucros_1.0 Primary Assembly

    Range
    709882..791038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029284097.1 → XP_029139930.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

    Conserved Domains (11) summary
    cd00275
    Location:1158 → 1282
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:389 → 536
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:733 → 835
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:615 → 719
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:861 → 919
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:935 → 1004
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:24 → 225
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd15898
    Location:230 → 259
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:230 → 376
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl14615
    Location:1048 → 1128
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl17171
    Location:559 → 593
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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