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NOA3 origin of replication NOA3 [ Homo sapiens (human) ]

Gene ID: 107228317, updated on 10-Oct-2023

Summary

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Gene symbol
NOA3
Gene description
origin of replication NOA3
Gene type
biological region
Feature type(s)
rep_origin
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This region contains an origin of DNA replication. This sequence can promote replication of a plasmid, and is also a site of initiation of nascent strand synthesis in its native genomic context. [provided by RefSeq, Feb 2016]
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Genomic context

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Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (31957197..31957548)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (32421306..32421658)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (32353184..32353535)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene YWHAH antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13642 Neighboring gene uncharacterized LOC124900477 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18873 Neighboring gene small nucleolar RNA U13 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18874 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18875 Neighboring gene long intergenic non-protein coding RNA 2558 Neighboring gene RNA, 7SL, cytoplasmic 305, pseudogene Neighboring gene ribosomal protein S17 pseudogene 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA clones contain autonomous replication activity. Wu C, et al. Biochim Biophys Acta, 1993 Sep 23. PMID 7690594
  2. Differential DNA replication origin activities in human normal skin fibroblast and HeLa cell lines. Tao L, et al. J Mol Biol, 1997 Oct 31. PMID 9356241

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Other Names

  • non-'O'-family, non-Alu homologous sequence NOA3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_046739.1 

    Range
    101..452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    31957197..31957548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    32421306..32421658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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