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PLCB2 phospholipase C beta 2 [ Parus major (Great Tit) ]

Gene ID: 107205812, updated on 3-Aug-2024

Summary

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Gene symbol
PLCB2
Gene description
phospholipase C beta 2
See related
Ensembl:ENSPMJG00000003350
Gene type
protein coding
RefSeq status
MODEL
Organism
Parus major
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Paridae; Parus
Orthologs
human mouse all
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Genomic context

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See PLCB2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
33
Annotation release Status Assembly Chr Location
102 current Parus_major1.1 (GCF_001522545.3) 5 NC_031774.1 (3621963..3662719, complement)
100 previous assembly Parus_major1.0.3 (GCF_001522545.1) 5 NC_029274.1 (3621963..3662716, complement)

Chromosome 5 - NC_031774.1Genomic Context describing neighboring genes Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene p21 (RAC1) activated kinase 6 Neighboring gene coiled-coil domain containing 9B Neighboring gene uncharacterized LOC107206130 Neighboring gene dispatched RND transporter family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Parus major Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Parus_major1.1 Primary Assembly

Genomic

  1. NC_031774.1 Reference Parus_major1.1 Primary Assembly

    Range
    3621963..3662719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033514929.1 → XP_033370820.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X2

    Conserved Domains (6) summary
    cd00275
    Location:783 → 904
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:415 → 751
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cl28895
    Location:192 → 403
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    pfam08703
    Location:1087 → 1260
    PLC-beta_C; PLC-beta C terminal
    pfam12474
    Location:1002 → 1158
    PKK; Polo kinase kinase
    pfam17787
    Location:97 → 184
    PH_14; PH domain

  2. XM_015630751.3 → XP_015486237.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X3

    Conserved Domains (8) summary
    cd00275
    Location:784 → 905
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:416 → 752
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:98 → 188
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:977 → 1012
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1070 → 1243
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:264 → 416
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam12474
    Location:985 → 1141
    PKK; Polo kinase kinase
    cl15454
    Location:1097 → 1223
    HrpJ; HrpJ-like domain

  3. XM_015630749.3 → XP_015486235.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1

    Conserved Domains (8) summary
    cd00275
    Location:784 → 905
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:416 → 752
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:98 → 188
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:995 → 1030
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1088 → 1261
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:264 → 416
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam12474
    Location:1003 → 1159
    PKK; Polo kinase kinase
    cl15454
    Location:1115 → 1241
    HrpJ; HrpJ-like domain

  4. XM_015630753.3 → XP_015486239.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X5

    Conserved Domains (9) summary
    cd00275
    Location:723 → 844
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:355 → 691
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    PLN02222
    Location:263 → 842
    PLN02222; phosphoinositide phospholipase C 2
    cd13361
    Location:98 → 188
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:934 → 969
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1027 → 1200
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:264 → 355
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam12474
    Location:942 → 1098
    PKK; Polo kinase kinase
    cl15454
    Location:1054 → 1180
    HrpJ; HrpJ-like domain

  5. XM_015630752.3 → XP_015486238.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X4

    Conserved Domains (8) summary
    cd00275
    Location:740 → 861
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:372 → 708
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:17 → 144
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:951 → 986
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1044 → 1217
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:220 → 372
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam12474
    Location:959 → 1115
    PKK; Polo kinase kinase
    cl15454
    Location:1071 → 1197
    HrpJ; HrpJ-like domain

  6. XM_015630754.3 → XP_015486240.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X6

    Related
    ENSPMJP00000003831.1, ENSPMJT00000005436.1
    Conserved Domains (9) summary
    cd00275
    Location:679 → 800
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 647
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    PLN02222
    Location:219 → 798
    PLN02222; phosphoinositide phospholipase C 2
    cd13361
    Location:17 → 144
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:890 → 925
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:983 → 1156
    PLC-beta_C; PLC-beta C terminal
    pfam09279
    Location:220 → 311
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    pfam12474
    Location:898 → 1054
    PKK; Polo kinase kinase
    cl15454
    Location:1010 → 1136
    HrpJ; HrpJ-like domain
Nucleotide Protein
Heading Accession and Version

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