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F12 coagulation factor XII [ Gekko japonicus ]

Gene ID: 107111529, updated on 14-Mar-2024

Summary

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Gene symbol
F12
Gene description
coagulation factor XII
Gene type
protein coding
RefSeq status
MODEL
Organism
Gekko japonicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Gekkota; Gekkonidae; Gekkoninae; Gekko
Orthologs
human mouse all
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Genomic context

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See F12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current Gekko_japonicus_V1.1 (GCF_001447785.1) Unplaced Scaffold NW_015167060.1 (425701..436749, complement)

NW_015167060.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 34 member 1 Neighboring gene alpha-2Db adrenergic receptor-like Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene proline rich 7, synaptic

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015167060.1 Unplaced Scaffold Reference Gekko_japonicus_V1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in rough endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
coagulation factor XII

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gekko japonicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gekko_japonicus_V1.1 Primary Assembly

Genomic

  1. NW_015167060.1 Reference Gekko_japonicus_V1.1 Primary Assembly

    Range
    425701..436749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015412500.1 → XP_015267986.1  coagulation factor XII

    Conserved Domains (6) summary
    smart00020
    Location:319 → 553
    Tryp_SPc; Trypsin-like serine protease
    smart00130
    Location:176 → 259
    KR; Kringle domain
    cd00054
    Location:60 → 91
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:320 → 556
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00008
    Location:139 → 168
    EGF; EGF-like domain
    pfam00040
    Location:8 → 49
    fn2; Fibronectin type II domain
Nucleotide Protein
Heading Accession and Version

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