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plecb plectin b [ Cyprinodon variegatus (sheepshead minnow) ]

Gene ID: 107100615, updated on 14-Mar-2024

Summary

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Gene symbol
plecb
Gene description
plectin b
See related
Ensembl:ENSCVAG00000013972
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyprinodon variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae; Cyprinodon
Orthologs
zebrafish all
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Genomic context

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See plecb in Genome Data Viewer
Location:
chromosome: Un
Exon count:
42
Annotation release Status Assembly Chr Location
100 current C_variegatus-1.0 (GCF_000732505.1) Unplaced Scaffold NW_015151446.1 (80841..220985, complement)

NW_015151446.1Genomic Context describing neighboring genes Neighboring gene riboflavin transporter 2-like Neighboring gene microtubule actin crosslinking factor 1b Neighboring gene hepcidin-like Neighboring gene sulfotransferase family 2, cytosolic sulfotransferase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015151446.1 Unplaced Scaffold Reference C_variegatus-1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ankyrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables keratin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of muscle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hemidesmosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intermediate filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in hemidesmosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in keratin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plectin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyprinodon variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C_variegatus-1.0 Primary Assembly

Genomic

  1. NW_015151446.1 Reference C_variegatus-1.0 Primary Assembly

    Range
    80841..220985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015399178.1 → XP_015254664.1  plectin-like isoform X11

    UniProtKB/TrEMBL
    A0A3Q2CZN7
    Related
    ENSCVAP00000011369.1, ENSCVAT00000018312.1
    Conserved Domains (15) summary
    smart00250
    Location:3442 → 3478
    PLEC; Plectin repeat
    cd00014
    Location:69 → 171
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:546 → 735
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:186 → 284
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4051 → 4092
    Plectin; Plectin repeat
    pfam01576
    Location:1363 → 2390
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2283 → 2611
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2539 → 2614
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2402 → 2416
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1142 → 1316
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:833 → 877
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2250 → 2351
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2323 → 2434
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1501 → 1622
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1671 → 1816
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  2. XM_015399176.1 → XP_015254662.1  plectin-like isoform X9

    UniProtKB/TrEMBL
    A0A3Q2CZN7
    Conserved Domains (15) summary
    smart00250
    Location:3467 → 3503
    PLEC; Plectin repeat
    cd00014
    Location:69 → 183
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:562 → 751
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:202 → 300
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4076 → 4117
    Plectin; Plectin repeat
    pfam01576
    Location:1388 → 2415
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2308 → 2636
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2564 → 2639
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2427 → 2441
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1167 → 1341
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:849 → 893
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2275 → 2376
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2348 → 2459
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1526 → 1647
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1696 → 1841
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  3. XM_015399179.1 → XP_015254665.1  plectin-like isoform X12

    UniProtKB/TrEMBL
    A0A3Q2CZM4
    Related
    ENSCVAP00000011354.1, ENSCVAT00000018288.1
    Conserved Domains (15) summary
    smart00250
    Location:3434 → 3470
    PLEC; Plectin repeat
    cd00014
    Location:36 → 150
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:529 → 718
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:169 → 267
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4043 → 4084
    Plectin; Plectin repeat
    pfam01576
    Location:1355 → 2382
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2275 → 2603
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2531 → 2606
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2394 → 2408
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1134 → 1308
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:816 → 860
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2242 → 2343
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2315 → 2426
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1493 → 1614
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1663 → 1808
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  4. XM_015399183.1 → XP_015254669.1  plectin-like isoform X16

    UniProtKB/TrEMBL
    A0A3Q2E511
    Conserved Domains (15) summary
    smart00250
    Location:3419 → 3455
    PLEC; Plectin repeat
    cd00014
    Location:21 → 135
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:514 → 703
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:154 → 252
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4028 → 4069
    Plectin; Plectin repeat
    pfam01576
    Location:1340 → 2367
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2260 → 2588
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2516 → 2591
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2379 → 2393
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1119 → 1293
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:801 → 845
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2227 → 2328
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2300 → 2411
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1478 → 1599
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1648 → 1793
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  5. XM_015399182.1 → XP_015254668.1  plectin-like isoform X15

    UniProtKB/TrEMBL
    A0A3Q2CZD6
    Related
    ENSCVAP00000011328.1, ENSCVAT00000018252.1
    Conserved Domains (15) summary
    smart00250
    Location:3425 → 3461
    PLEC; Plectin repeat
    cd00014
    Location:27 → 141
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:520 → 709
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:160 → 258
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4034 → 4075
    Plectin; Plectin repeat
    pfam01576
    Location:1346 → 2373
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2266 → 2594
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2522 → 2597
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2385 → 2399
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1125 → 1299
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:807 → 851
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2233 → 2334
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2306 → 2417
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1484 → 1605
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1654 → 1799
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  6. XM_015399167.1 → XP_015254653.1  plectin-like isoform X1

    Conserved Domains (16) summary
    smart00250
    Location:4719 → 4755
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1814 → 2003
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1454 → 1552
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5328 → 5369
    Plectin; Plectin repeat
    pfam01576
    Location:2640 → 3667
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3560 → 3888
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3816 → 3891
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3679 → 3693
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2419 → 2593
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2101 → 2145
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3527 → 3628
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3600 → 3711
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2778 → 2899
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2948 → 3093
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  7. XM_015399168.1 → XP_015254654.1  plectin-like isoform X2

    Conserved Domains (16) summary
    smart00250
    Location:4715 → 4751
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1810 → 1999
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1450 → 1548
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5324 → 5365
    Plectin; Plectin repeat
    pfam01576
    Location:2636 → 3663
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3556 → 3884
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3812 → 3887
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3675 → 3689
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2415 → 2589
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2097 → 2141
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3523 → 3624
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3596 → 3707
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2774 → 2895
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2944 → 3089
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  8. XM_015399166.1 → XP_015254652.1  plectin-like isoform X1

    Conserved Domains (16) summary
    smart00250
    Location:4719 → 4755
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1814 → 2003
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1454 → 1552
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5328 → 5369
    Plectin; Plectin repeat
    pfam01576
    Location:2640 → 3667
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3560 → 3888
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3816 → 3891
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3679 → 3693
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2419 → 2593
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2101 → 2145
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3527 → 3628
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3600 → 3711
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2778 → 2899
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2948 → 3093
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  9. XM_015399172.1 → XP_015254658.1  plectin-like isoform X6

    Conserved Domains (16) summary
    smart00250
    Location:4694 → 4730
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1423
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1798 → 1987
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1438 → 1536
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5303 → 5344
    Plectin; Plectin repeat
    pfam01576
    Location:2615 → 3642
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3535 → 3863
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3791 → 3866
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3654 → 3668
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2394 → 2568
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2085 → 2129
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3502 → 3603
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3575 → 3686
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2753 → 2874
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2923 → 3068
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  10. XM_015399171.1 → XP_015254657.1  plectin-like isoform X5

    UniProtKB/TrEMBL
    A0A3Q2CZF4
    Related
    ENSCVAP00000011312.1, ENSCVAT00000018248.1
    Conserved Domains (16) summary
    smart00250
    Location:4698 → 4734
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1423
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1802 → 1991
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1442 → 1540
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5307 → 5348
    Plectin; Plectin repeat
    pfam01576
    Location:2619 → 3646
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3539 → 3867
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3795 → 3870
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3658 → 3672
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2398 → 2572
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2089 → 2133
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3506 → 3607
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3579 → 3690
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2757 → 2878
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2927 → 3072
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  11. XM_015399170.1 → XP_015254656.1  plectin-like isoform X4

    Conserved Domains (16) summary
    smart00250
    Location:4707 → 4743
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1423
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1802 → 1991
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1442 → 1540
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5316 → 5357
    Plectin; Plectin repeat
    pfam01576
    Location:2628 → 3655
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3548 → 3876
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3804 → 3879
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3667 → 3681
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2407 → 2581
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2089 → 2133
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3515 → 3616
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3588 → 3699
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2766 → 2887
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2936 → 3081
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  12. XM_015399169.1 → XP_015254655.1  plectin-like isoform X3

    Conserved Domains (16) summary
    smart00250
    Location:4710 → 4746
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1814 → 2003
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1454 → 1552
    CH; Calponin homology (CH) domain
    pfam00681
    Location:5319 → 5360
    Plectin; Plectin repeat
    pfam01576
    Location:2631 → 3658
    Myosin_tail_1; Myosin tail
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13868
    Location:3551 → 3879
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:3807 → 3882
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:3670 → 3684
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:2410 → 2584
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:2101 → 2145
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:3518 → 3619
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:3591 → 3702
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:2769 → 2890
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:2939 → 3084
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  13. XM_015399173.1 → XP_015254659.1  plectin-like isoform X7

    Conserved Domains (10) summary
    smart00250
    Location:3601 → 3637
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1814 → 2003
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1454 → 1552
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4210 → 4251
    Plectin; Plectin repeat
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13879
    Location:2698 → 2773
    KIAA1430; KIAA1430 homologue
    cl02488
    Location:2317 → 2505
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl12013
    Location:2570 → 2749
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl17036
    Location:2101 → 2145
    SH3; Src Homology 3 domain superfamily

  14. XM_015399175.1 → XP_015254661.1  plectin-like isoform X8

    Conserved Domains (10) summary
    smart00250
    Location:3592 → 3628
    PLEC; Plectin repeat
    cd00014
    Location:1321 → 1435
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1814 → 2003
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:1454 → 1552
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4201 → 4242
    Plectin; Plectin repeat
    pfam03501
    Location:7 → 101
    S10_plectin; Plectin/S10 domain
    pfam13879
    Location:2689 → 2764
    KIAA1430; KIAA1430 homologue
    cl02488
    Location:2308 → 2496
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl12013
    Location:2561 → 2740
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl17036
    Location:2101 → 2145
    SH3; Src Homology 3 domain superfamily

  15. XM_015399185.1 → XP_015254671.1  plectin-like isoform X18

    UniProtKB/TrEMBL
    A0A3Q2E511
    Related
    ENSCVAP00000027328.1, ENSCVAT00000018235.1
    Conserved Domains (15) summary
    smart00250
    Location:3409 → 3445
    PLEC; Plectin repeat
    cd00014
    Location:11 → 125
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:504 → 693
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:144 → 242
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4018 → 4059
    Plectin; Plectin repeat
    pfam01576
    Location:1330 → 2357
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2250 → 2578
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2506 → 2581
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2369 → 2383
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1109 → 1283
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:791 → 835
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2217 → 2318
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2290 → 2401
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1468 → 1589
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1638 → 1783
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  16. XM_015399184.1 → XP_015254670.1  plectin-like isoform X17

    UniProtKB/TrEMBL
    A0A3Q2GJ95
    Related
    ENSCVAP00000027295.1, ENSCVAT00000029867.1
    Conserved Domains (15) summary
    smart00250
    Location:3418 → 3454
    PLEC; Plectin repeat
    cd00014
    Location:45 → 147
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:522 → 711
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:162 → 260
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4027 → 4068
    Plectin; Plectin repeat
    pfam01576
    Location:1339 → 2366
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2259 → 2587
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2515 → 2590
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2378 → 2392
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1118 → 1292
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:809 → 853
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2226 → 2327
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2299 → 2410
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1477 → 1598
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1647 → 1792
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  17. XM_015399181.1 → XP_015254667.1  plectin-like isoform X14

    UniProtKB/TrEMBL
    A0A3Q2GJ95
    Conserved Domains (15) summary
    smart00250
    Location:3427 → 3463
    PLEC; Plectin repeat
    cd00014
    Location:45 → 147
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:522 → 711
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:162 → 260
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4036 → 4077
    Plectin; Plectin repeat
    pfam01576
    Location:1348 → 2375
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2268 → 2596
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2524 → 2599
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2387 → 2401
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1127 → 1301
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:809 → 853
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2235 → 2336
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2308 → 2419
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1486 → 1607
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1656 → 1801
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  18. XM_015399180.1 → XP_015254666.1  plectin-like isoform X13

    UniProtKB/TrEMBL
    A0A3Q2GJ95
    Conserved Domains (15) summary
    smart00250
    Location:3431 → 3467
    PLEC; Plectin repeat
    cd00014
    Location:45 → 147
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:526 → 715
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:166 → 264
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4040 → 4081
    Plectin; Plectin repeat
    pfam01576
    Location:1352 → 2379
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2272 → 2600
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2528 → 2603
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2391 → 2405
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1131 → 1305
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:813 → 857
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2239 → 2340
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2312 → 2423
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1490 → 1611
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1660 → 1805
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  19. XM_015399177.1 → XP_015254663.1  plectin-like isoform X10

    UniProtKB/TrEMBL
    A0A3Q2GJ95
    Conserved Domains (15) summary
    smart00250
    Location:3443 → 3479
    PLEC; Plectin repeat
    cd00014
    Location:45 → 159
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:538 → 727
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:178 → 276
    CH; Calponin homology (CH) domain
    pfam00681
    Location:4052 → 4093
    Plectin; Plectin repeat
    pfam01576
    Location:1364 → 2391
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2284 → 2612
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2540 → 2615
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2403 → 2417
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:1143 → 1317
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:825 → 869
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2251 → 2352
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2324 → 2435
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1502 → 1623
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1672 → 1817
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

  20. XM_015399186.1 → XP_015254672.1  plectin-like isoform X19

    UniProtKB/TrEMBL
    A0A3Q2E511
    Conserved Domains (14) summary
    smart00250
    Location:3219 → 3255
    PLEC; Plectin repeat
    cd00176
    Location:314 → 503
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00307
    Location:6 → 52
    CH; Calponin homology (CH) domain
    pfam00681
    Location:3828 → 3869
    Plectin; Plectin repeat
    pfam01576
    Location:1140 → 2167
    Myosin_tail_1; Myosin tail
    pfam13868
    Location:2060 → 2388
    TPH; Trichohyalin-plectin-homology domain
    pfam13879
    Location:2316 → 2391
    KIAA1430; KIAA1430 homologue
    cd16269
    Location:2179 → 2193
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:919 → 1093
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17036
    Location:601 → 645
    SH3; Src Homology 3 domain superfamily
    cl19107
    Location:2027 → 2128
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    cl20817
    Location:2100 → 2211
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21478
    Location:1278 → 1399
    ATP-synt_B; ATP synthase B/B' CF(0)
    cl23750
    Location:1448 → 1593
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
Nucleotide Protein
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