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capn3a calpain 3a, (p94) [ Cyprinodon variegatus (sheepshead minnow) ]

Gene ID: 107096801, updated on 14-Mar-2024

Summary

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Gene symbol
capn3a
Gene description
calpain 3a, (p94)
See related
Ensembl:ENSCVAG00000006244
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyprinodon variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Cyprinodontidae; Cyprinodon
Also known as
capn3
Orthologs
human zebrafish all
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Genomic context

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See capn3a in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
100 current C_variegatus-1.0 (GCF_000732505.1) Unplaced Scaffold NW_015151103.1 (400422..421090, complement)

NW_015151103.1Genomic Context describing neighboring genes Neighboring gene proton activated chloride channel 1 Neighboring gene zinc finger protein 106a Neighboring gene glucosidase, alpha; neutral C Neighboring gene transmembrane protein 87A-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015151103.1 Unplaced Scaffold Reference C_variegatus-1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3
Names
calpain 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyprinodon variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C_variegatus-1.0 Primary Assembly

Genomic

  1. NW_015151103.1 Reference C_variegatus-1.0 Primary Assembly

    Range
    400422..421090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015393621.1 → XP_015249107.1  calpain-3 isoform X1

    Conserved Domains (4) summary
    COG5126
    Location:619 → 715
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam00648
    Location:51 → 351
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:365 → 515
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:589 → 646
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_015393622.1 → XP_015249108.1  calpain-3 isoform X2

    Conserved Domains (5) summary
    COG5126
    Location:616 → 712
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd00051
    Location:589 → 643
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:51 → 351
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:365 → 515
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:560 → 613
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  3. XM_015393623.1 → XP_015249109.1  calpain-3 isoform X3

    Conserved Domains (3) summary
    pfam00648
    Location:51 → 351
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:365 → 515
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:589 → 646
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  4. XM_015393624.1 → XP_015249110.1  calpain-3 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2FK52
    Related
    ENSCVAP00000004935.1, ENSCVAT00000007526.1
    Conserved Domains (4) summary
    cd00051
    Location:589 → 643
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:51 → 351
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:365 → 515
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:560 → 613
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

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