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TDP2 tyrosyl-DNA phosphodiesterase 2 [ Calidris pugnax (ruff) ]

Gene ID: 106885971, updated on 3-Aug-2024

Summary

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Gene symbol
TDP2
Gene description
tyrosyl-DNA phosphodiesterase 2
See related
Ensembl:ENSCPUG00000006350
Gene type
protein coding
RefSeq status
MODEL
Organism
Calidris pugnax
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Scolopacidae; Calidris
Orthologs
human mouse all
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Genomic context

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See TDP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current ASM143184v1 (GCF_001431845.1) Unplaced Scaffold NW_015090810.1 (9928396..9950076)

NW_015090810.1Genomic Context describing neighboring genes Neighboring gene RHO family interacting cell polarization regulator 2 Neighboring gene chromosome unknown open reading frame, human C6orf62 Neighboring gene geminin DNA replication inhibitor Neighboring gene acyl-CoA thioesterase 13 Neighboring gene galanin receptor 1 Neighboring gene myelin basic protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015090810.1 Unplaced Scaffold Reference ASM143184v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosyl-DNA phosphodiesterase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Calidris pugnax Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM143184v1

Genomic

  1. NW_015090810.1 Reference ASM143184v1

    Range
    9928396..9950076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014938501.1 → XP_014793987.1  tyrosyl-DNA phosphodiesterase 2 isoform X2

    Conserved Domains (1) summary
    cd09080
    Location:86 → 330
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains

  2. XM_014938504.1 → XP_014793990.1  tyrosyl-DNA phosphodiesterase 2 isoform X4

    Conserved Domains (1) summary
    cd09080
    Location:66 → 310
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains

  3. XM_014938502.1 → XP_014793988.1  tyrosyl-DNA phosphodiesterase 2 isoform X3

    Conserved Domains (1) summary
    cd09080
    Location:70 → 314
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains

  4. XM_014938500.1 → XP_014793986.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    Related
    ENSCPUP00000008895.1, ENSCPUT00000010625.1
    Conserved Domains (2) summary
    cd09080
    Location:138 → 382
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:52 → 87
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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