U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ALOX12 arachidonate 12-lipoxygenase, 12S type [ Equus asinus (ass) ]

Gene ID: 106844160, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
ALOX12
Gene description
arachidonate 12-lipoxygenase, 12S type
See related
Ensembl:ENSEASG00005017902
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ALOX12 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 13 NC_052189.1 (14729238..14741647, complement)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638249.1 (405325..418455)

Chromosome 13 - NC_052189.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123275926 Neighboring gene uncharacterized LOC106844164 Neighboring gene BPTF associated chromatin complex component 1 Neighboring gene ribonuclease K Neighboring gene polyunsaturated fatty acid lipoxygenase ALOX12-like Neighboring gene polyunsaturated fatty acid lipoxygenase ALOX12-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
polyunsaturated fatty acid lipoxygenase ALOX12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052189.1 Reference ASM1607732v2

    Range
    14729238..14741647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014861467.2 → XP_014716953.2  polyunsaturated fatty acid lipoxygenase ALOX12

    UniProtKB/TrEMBL
    A0A8C4MIG7, A0A9L0JL14
    Related
    ENSEASP00005049880.1, ENSEAST00005048715.1
    Conserved Domains (2) summary
    PLN02305
    Location:222 → 663
    PLN02305; lipoxygenase
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.