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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Equus asinus (ass) ]

Gene ID: 106825003, updated on 13-Mar-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSEASG00005013500
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See HMGCS1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 10 NC_052186.1 (56083656..56103960)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014636980.1 (1679734..1701120)

Chromosome 10 - NC_052186.1Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine ligand 28 Neighboring gene uncharacterized LOC123289431 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene zinc finger protein 131

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052186.1 Reference ASM1607732v2

    Range
    56083656..56103960
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044779363.1 → XP_044635298.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Related
    ENSEASP00005019640.1, ENSEAST00005021306.2
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_014831569.2 → XP_014687055.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  3. XM_014831585.2 → XP_014687071.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  4. XM_044779364.1 → XP_044635299.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  5. XM_044779362.1 → XP_044635297.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  6. XM_014831578.2 → XP_014687064.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A8C4M434, A0A8C4M721
    Conserved Domains (1) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
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