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LOC106783504 conserved acetylation island sequence C15 enhancer [ Homo sapiens (human) ]

Gene ID: 106783504, updated on 10-Oct-2023

Summary

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Gene symbol
LOC106783504
Gene description
conserved acetylation island sequence C15 enhancer
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This region, which is conserved between human and pufferfish and which overlaps the poly(rC) binding protein 1 (PCBP1) gene on chromosome 2, can function as an enhancer in human Jurkat T cells. Its chromatin structure represents a histone acetylation island in human T cells based on the diacetylation of histone H3 at lysines 9 and 14. [provided by RefSeq, Nov 2015]
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Genomic context

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Location:
2p13-p12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (70088615..70088781)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (70100339..70100505)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (70315747..70315913)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene aspartic peptidase retroviral like 1 Neighboring gene small nucleolar RNA U13 Neighboring gene Sharpr-MPRA regulatory region 1834 Neighboring gene PCBP1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70199285-70200162 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70202867-70203378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70203379-70203889 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70211622-70212122 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70212123-70212623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70220299-70220798 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:70224580-70224834 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15983 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:70256223-70257094 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15984 Neighboring gene Sharpr-MPRA regulatory region 12254 Neighboring gene RNA, 7SL, cytoplasmic 470, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15986 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15987 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15988 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11604 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70315031-70315675 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11605 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11606 Neighboring gene uncharacterized LOC124906022 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15989 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15990 Neighboring gene poly(rC) binding protein 1 Neighboring gene mitochondrial ribosomal protein L36 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns. Roh TY, et al. Genome Res, 2007 Jan. PMID 17135569, Free PMC Article
  2. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Roh TY, et al. Genes Dev, 2005 Mar 1. PMID 15706033, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Other Names

  • conserved AI C15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_046088.1 

    Range
    101..267
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    70088615..70088781
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    70100339..70100505
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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