U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CAPN3 calpain 3 [ Thamnophis sirtalis ]

Gene ID: 106547747, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
CAPN3
Gene description
calpain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Thamnophis sirtalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CAPN3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current Thamnophis_sirtalis-6.0 (GCF_001077635.1) Unplaced Scaffold NW_013658723.1 (353410..394278)

NW_013658723.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_013658723.1 Unplaced Scaffold Reference Thamnophis_sirtalis-6.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Thamnophis sirtalis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Thamnophis_sirtalis-6.0

Genomic

  1. NW_013658723.1 Reference Thamnophis_sirtalis-6.0

    Range
    353410..394278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014064998.1 → XP_013920473.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A6I9Y681
    Conserved Domains (4) summary
    cd00051
    Location:641 → 696
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:69 → 405
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:419 → 569
    Calpain_III; Calpain large subunit, domain III
    cl08302
    Location:672 → 761
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_014064999.1 → XP_013920474.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A6I9XWA5
    Conserved Domains (5) summary
    cd00051
    Location:602 → 657
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:69 → 361
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:375 → 525
    Calpain_III; Calpain large subunit, domain III
    pfam13499
    Location:560 → 625
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:633 → 722
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.