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ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [ Sus scrofa (pig) ]

Gene ID: 106509950, updated on 17-Aug-2024

Summary

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Official Symbol
ASAP1provided by VGNC
Official Full Name
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1provided by VGNC
Primary source
VGNC:VGNC:98734
See related
Ensembl:ENSSSCG00000028759
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in ovary (RPKM 19.7), spleen (RPKM 6.0) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See ASAP1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
34
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 4 NC_010446.5 (10103860..10451928)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 4 NC_010446.4 (10385433..10423543)

Chromosome 4 - NC_010446.5Genomic Context describing neighboring genes Neighboring gene otoconin 90 Neighboring gene EFR3 homolog A Neighboring gene adenylate cyclase 8 Neighboring gene uncharacterized LOC102163032 Neighboring gene gasdermin-A-like Neighboring gene CYFIP related Rac1 interactor B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Names
differentiation enhancing factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010446.5 Reference Sscrofa11.1 Primary Assembly

    Range
    10103860..10451928
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021088910.1 → XP_020944569.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:604 → 692
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:319 → 425
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:604 → 637
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:442 → 558
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1070 → 1104
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:727 → 1059
    Atrophin-1; Atrophin-1 family

  2. XM_021088909.1 → XP_020944568.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A4X1SUW7, A0A8D0HY96, A0A8D0RYM0
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1067 → 1123
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:601 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:316 → 422
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:601 → 634
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:439 → 555
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:724 → 1056
    Atrophin-1; Atrophin-1 family

  3. XM_021088906.1 → XP_020944565.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:604 → 692
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:319 → 425
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:604 → 637
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:442 → 558
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1070 → 1106
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:727 → 1059
    Atrophin-1; Atrophin-1 family

  4. XM_021088908.1 → XP_020944567.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A4X1SUW7
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1070 → 1126
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:604 → 692
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:319 → 425
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:604 → 637
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:442 → 558
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:727 → 1059
    Atrophin-1; Atrophin-1 family

  5. XM_021088915.1 → XP_020944574.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:604 → 692
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:319 → 425
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:604 → 637
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:442 → 558
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1013 → 1049
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:730 → 1002
    Atrophin-1; Atrophin-1 family

  6. XM_021088917.1 → XP_020944576.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A8D0LEY7, A0A8D0S7G6
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1013 → 1069
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:604 → 692
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:319 → 425
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:604 → 637
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:442 → 558
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:730 → 1002
    Atrophin-1; Atrophin-1 family

  7. XM_021088907.1 → XP_020944566.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A287B2W2, A0A8D1QS27, A0A8D1TCR6, A0A8D1ZEI1
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:601 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:316 → 422
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:601 → 634
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:439 → 555
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1067 → 1103
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:724 → 1056
    Atrophin-1; Atrophin-1 family

  8. XM_021088916.1 → XP_020944575.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A8D1EW17, A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:601 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:316 → 422
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:601 → 634
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:439 → 555
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1010 → 1046
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:727 → 999
    Atrophin-1; Atrophin-1 family

  9. XM_021088918.1 → XP_020944577.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A8D0LEY7, A0A8D0S0U5, A0A8D0S7G6
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1010 → 1066
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:601 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:316 → 422
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:601 → 634
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:439 → 555
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:727 → 999
    Atrophin-1; Atrophin-1 family

  10. XM_021088911.1 → XP_020944570.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:34 → 248
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:584 → 672
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:299 → 405
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:584 → 617
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:422 → 538
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1050 → 1086
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:707 → 1039
    Atrophin-1; Atrophin-1 family

  11. XM_021088912.1 → XP_020944571.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8D1QS27
    Conserved Domains (7) summary
    cd07641
    Location:34 → 248
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd00204
    Location:581 → 669
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:296 → 402
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:581 → 614
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:419 → 535
    ArfGap; Putative GTPase activating protein for Arf
    cl17036
    Location:1047 → 1083
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:704 → 1036
    Atrophin-1; Atrophin-1 family

  12. XM_021088919.1 → XP_020944578.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A8D0LEB0, A0A8D0LEY7, A0A8D0S7G6
    Conserved Domains (7) summary
    cd07641
    Location:34 → 248
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:990 → 1046
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:581 → 669
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:296 → 402
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:581 → 614
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:419 → 535
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:707 → 979
    Atrophin-1; Atrophin-1 family

  13. XM_021088913.1 → XP_020944572.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8D1M349, A0A8D1QSL9, A0A8D1ZEH1
    Related
    ENSSSCP00000051771.2, ENSSSCT00000041003.2
    Conserved Domains (7) summary
    cd07641
    Location:34 → 248
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1047 → 1103
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:581 → 669
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:296 → 402
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:581 → 614
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:419 → 535
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:704 → 1036
    Atrophin-1; Atrophin-1 family

  14. XM_021088914.1 → XP_020944573.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A8D0I5V5
    Conserved Domains (7) summary
    cd00204
    Location:577 → 665
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:292 → 398
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:577 → 610
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:415 → 531
    ArfGap; Putative GTPase activating protein for Arf
    cl12013
    Location:34 → 241
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl17036
    Location:1043 → 1079
    SH3; Src Homology 3 domain superfamily
    cl26464
    Location:700 → 1032
    Atrophin-1; Atrophin-1 family

RNA

  1. XR_002343078.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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