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RFC4 replication factor C subunit 4 [ Sus scrofa (pig) ]

Gene ID: 106504063, updated on 17-Aug-2024

Summary

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Official Symbol
RFC4provided by VGNC
Official Full Name
replication factor C subunit 4provided by VGNC
Primary source
VGNC:VGNC:92234
See related
Ensembl:ENSSSCG00000011804
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in ovary (RPKM 64.5), spleen (RPKM 13.8) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See RFC4 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (124589292..124604421, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (133979667..133994796, complement)

Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene histidine rich glycoprotein Neighboring gene kininogen 1 Neighboring gene eukaryotic translation initiation factor 4A2 Neighboring gene adiponectin, C1Q and collagen domain containing Neighboring gene uncharacterized LOC102158991 Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA clamp loader activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication factor C complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
replication factor C subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

    Range
    124589292..124604421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013988325.2 → XP_013843779.1  replication factor C subunit 4 isoform X2

    UniProtKB/TrEMBL
    A0A8D0KFP5
    Conserved Domains (3) summary
    cd00009
    Location:55 → 201
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    PRK00440
    Location:39 → 312
    rfc; replication factor C small subunit; Reviewed
    pfam08542
    Location:243 → 312
    Rep_fac_C; Replication factor C C-terminal domain

  2. XM_005652371.3 → XP_005652428.1  replication factor C subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A4X1UGI7, A0A4X1UGJ2, F1SFI3
    Related
    ENSSSCP00000012575.3, ENSSSCT00000012916.4
    Conserved Domains (1) summary
    cl25702
    Location:39 → 354
    Rad17; Rad17 cell cycle checkpoint protein

  3. XM_021070017.1 → XP_020925676.1  replication factor C subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A4X1UGI7, A0A4X1UGJ2, F1SFI3
    Conserved Domains (1) summary
    cl25702
    Location:39 → 354
    Rad17; Rad17 cell cycle checkpoint protein

  4. XM_021070018.1 → XP_020925677.1  replication factor C subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A4X1UGI7, A0A4X1UGJ2, F1SFI3
    Conserved Domains (1) summary
    cl25702
    Location:39 → 354
    Rad17; Rad17 cell cycle checkpoint protein
Nucleotide Protein
Heading Accession and Version

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