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LOC106465096 E3 ubiquitin-protein ligase CBL-like [ Limulus polyphemus (Atlantic horseshoe crab) ]

Gene ID: 106465096, updated on 21-Dec-2023

Summary

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Gene symbol
LOC106465096
Gene description
E3 ubiquitin-protein ligase CBL-like
See related
EnsemblRapid:LOC106465096
Gene type
protein coding
RefSeq status
MODEL
Organism
Limulus polyphemus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Merostomata; Xiphosura; Limulidae; Limulus
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Genomic context

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See LOC106465096 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Limulus_polyphemus-2.1.2 (GCF_000517525.1) Unplaced Scaffold NW_013667444.1 (5349..78950)

NW_013667444.1Genomic Context describing neighboring genes Neighboring gene dixin-A-like Neighboring gene homeobox protein PKNOX2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_013667444 Unplaced Scaffold Reference Limulus_polyphemus-2.1.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Limulus polyphemus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Limulus_polyphemus-2.1.2 Primary Assembly

Genomic

  1. NW_013667444.1 Reference Limulus_polyphemus-2.1.2 Primary Assembly

    Range
    5349..78950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013925292.2 → XP_013780746.1  E3 ubiquitin-protein ligase CBL-like

    Related
    XP_013780746.1, XM_013925292.2
    Conserved Domains (5) summary
    cd09920
    Location:243 → 338
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd00162
    Location:367 → 409
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd14318
    Location:753 → 791
    UBA_Cbl_like; UBA domain found in casitas B-lineage lymphoma (Cbl) proteins
    pfam02262
    Location:40 → 161
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:165 → 248
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein
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