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CRKL CRK like proto-oncogene, adaptor protein [ Anser cygnoides (Swan goose) ]

Gene ID: 106031307, updated on 7-Aug-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
See related
EnsemblRapid:ENSACDG00000001279
Gene type
protein coding
RefSeq status
MODEL
Organism
Anser cygnoides
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Anser
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: 17
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_07 current Taihu_goose_T2T_genome (GCF_040182565.1) 17 NC_089889.1 (10293392..10310629, complement)
100 previous assembly GooseV1.0 (GCF_002166845.1) Unplaced Scaffold NW_025927689.1 (3578987..3596254)

Chromosome 17 - NC_089889.1Genomic Context describing neighboring genes Neighboring gene calcineurin binding protein 1 Neighboring gene uncharacterized LOC106031302 Neighboring gene T-box-containing protein TBX6L Neighboring gene uncharacterized LOC106031308 Neighboring gene uncharacterized LOC136786532 Neighboring gene kelch like family member 22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_040182565.1-RS_2024_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Taihu_goose_T2T_genome Primary Assembly

Genomic

  1. NC_089889.1 Reference Taihu_goose_T2T_genome Primary Assembly

    Range
    10293392..10310629 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013173604.3 → XP_013029058.1  crk-like protein

    UniProtKB/TrEMBL
    A0A8B9EKM0
    Related
    ENSACDP00000002055.1
    Conserved Domains (3) summary
    cd09926
    Location:7 → 107
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:235 → 291
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
Nucleotide Protein
Heading Accession and Version

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