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hic1 hypermethylated in cancer 1 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105934543, updated on 20-Aug-2024

Summary

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Gene symbol
hic1
Gene description
hypermethylated in cancer 1
See related
EnsemblRapid:ENSFHEG00000003606
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Orthologs
human zebrafish all
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Genomic context

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See hic1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
3
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 18 NC_046378.1 (27766788..27782634)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234404.1 (247857..263947)

Chromosome 18 - NC_046378.1Genomic Context describing neighboring genes Neighboring gene TAO kinase 1a Neighboring gene TSR1 ribosome maturation factor Neighboring gene uncharacterized LOC118566736 Neighboring gene diphthamide biosynthesis 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypermethylated in cancer 1 protein
Names
B-cell lymphoma 6 protein
HIC ZBTB transcriptional repressor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046378.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    27766788..27782634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012874590.3 → XP_012730044.2  hypermethylated in cancer 1 protein isoform X3

    UniProtKB/TrEMBL
    A0A3Q2NU14
    Related
    ENSFHEP00000062167.1, ENSFHET00000046074.1
    Conserved Domains (4) summary
    sd00017
    Location:551 → 571
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:7 → 129
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
    pfam00096
    Location:549 → 571
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:591 → 616
    zf-H2C2_2; Zinc-finger double domain

  2. XM_012874589.3 → XP_012730043.2  hypermethylated in cancer 1 protein isoform X1

    UniProtKB/TrEMBL
    A0A3Q2NU14
    Related
    ENSFHEP00000002789.2, ENSFHET00000011641.2
    Conserved Domains (4) summary
    sd00017
    Location:574 → 594
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:30 → 152
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
    pfam00096
    Location:572 → 594
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:614 → 639
    zf-H2C2_2; Zinc-finger double domain

  3. XM_036150298.1 → XP_036006191.1  hypermethylated in cancer 1 protein isoform X2

    UniProtKB/TrEMBL
    A0A3Q2NU14
    Conserved Domains (4) summary
    sd00017
    Location:564 → 584
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:20 → 142
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
    pfam00096
    Location:562 → 584
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:604 → 629
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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