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LOC105902465 TNF receptor-associated factor 2 [ Clupea harengus (Atlantic herring) ]

Gene ID: 105902465, updated on 18-Jun-2024

Summary

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Gene symbol
LOC105902465
Gene description
TNF receptor-associated factor 2
See related
Ensembl:ENSCHAG00020012264
Gene type
protein coding
RefSeq status
MODEL
Organism
Clupea harengus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei; Clupeidae; Clupea
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Genomic context

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See LOC105902465 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
13
Annotation release Status Assembly Chr Location
102 current Ch_v2.0.2 (GCF_900700415.2) 12 NC_045163.1 (21269278..21277845)

Chromosome 12 - NC_045163.1Genomic Context describing neighboring genes Neighboring gene apical junction component 1 homolog Neighboring gene RAB, member RAS oncogene family-like 6a Neighboring gene tenascin-like Neighboring gene tenascin Ca Neighboring gene uncharacterized LOC116222780

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045163.1 Chromosome 12 Reference Ch_v2.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Clupea harengus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ch_v2.0.2 Primary Assembly

Genomic

  1. NC_045163.1 Reference Ch_v2.0.2 Primary Assembly

    Range
    21269278..21277845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031577122.2 → XP_031432982.2  TNF receptor-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P8GBS2
    Conserved Domains (4) summary
    TIGR00599
    Location:34 → 157
    rad18; DNA repair protein rad18
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:435 → 530
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    cl40617
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger

  2. XM_031577121.2 → XP_031432981.2  TNF receptor-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P8GBS2
    Conserved Domains (4) summary
    TIGR00599
    Location:34 → 157
    rad18; DNA repair protein rad18
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:435 → 530
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    cl40617
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger

  3. XM_012830053.2 → XP_012685507.2  TNF receptor-associated factor 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P3W082
    Related
    ENSCHAP00020026514.1, ENSCHAT00020028643.1
    Conserved Domains (5) summary
    TIGR00599
    Location:50 → 173
    rad18; DNA repair protein rad18
    pfam02176
    Location:194 → 251
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:48 → 89
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:451 → 612
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:382 → 444
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
Nucleotide Protein
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