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LARGE2 LARGE xylosyl- and glucuronyltransferase 2 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105885250, updated on 13-Mar-2024

Summary

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Gene symbol
LARGE2
Gene description
LARGE xylosyl- and glucuronyltransferase 2
See related
Ensembl:ENSMICG00000014226
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See LARGE2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 5 NC_033664.1 (19694552..19700524, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195453.1 (2021123..2030231, complement)

Chromosome 5 - NC_033664.1Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase zeta Neighboring gene cAMP responsive element binding protein 3 like 1 Neighboring gene PHD finger protein 21A Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene Frey regulator of sperm-oocyte fusion 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LARGE xylosyl- and glucuronyltransferase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033664.1 Reference Mmur_3.0 Primary Assembly

    Range
    19694552..19700524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020286499.1 → XP_020142088.1  LARGE xylosyl- and glucuronyltransferase 2 isoform X3

    UniProtKB/TrEMBL
    A0A8B7X4F6
    Conserved Domains (2) summary
    cd06431
    Location:65 → 420
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:473 → 689
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  2. XM_020286498.1 → XP_020142087.1  LARGE xylosyl- and glucuronyltransferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8B7X302
    Conserved Domains (2) summary
    cd06431
    Location:65 → 420
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:473 → 706
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  3. XM_012790046.1 → XP_012645500.1  LARGE xylosyl- and glucuronyltransferase 2 isoform X4

    UniProtKB/TrEMBL
    A0A8B7I3X3
    Related
    ENSMICP00000012978.3, ENSMICT00000014236.3
    Conserved Domains (3) summary
    cd06431
    Location:65 → 344
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    COG1442
    Location:66 → 313
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    pfam13896
    Location:397 → 630
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  4. XM_012790041.2 → XP_012645495.1  LARGE xylosyl- and glucuronyltransferase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8B7I3W8
    Conserved Domains (3) summary
    cd06431
    Location:96 → 375
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    COG1442
    Location:97 → 344
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    pfam13896
    Location:428 → 661
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
Nucleotide Protein
Heading Accession and Version

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