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SC5D sterol-C5-desaturase [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105885179, updated on 13-Mar-2024

Summary

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Gene symbol
SC5D
Gene description
sterol-C5-desaturase
See related
Ensembl:ENSMICG00000011243
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See SC5D in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 5 NC_033664.1 (102144196..102154653)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012198541.1 (2483162..2493616, complement)

Chromosome 5 - NC_033664.1Genomic Context describing neighboring genes Neighboring gene tubulin folding cofactor E like Neighboring gene tectorin alpha Neighboring gene sortilin related receptor 1 Neighboring gene uncharacterized LOC105885177

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process via lathosterol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lathosterol oxidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033664.1 Reference Mmur_3.0 Primary Assembly

    Range
    102144196..102154653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012789892.2 → XP_012645346.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645346.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Related
    ENSMICP00000010234.2, ENSMICT00000011235.3
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  2. XM_012789894.1 → XP_012645348.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645348.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  3. XM_012789897.1 → XP_012645351.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645351.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  4. XM_012789899.1 → XP_012645353.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645353.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  5. XM_012789895.1 → XP_012645349.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645349.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Related
    ENSMICP00000019677.1, ENSMICT00000050428.2
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  6. XM_012789898.2 → XP_012645352.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645352.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily

  7. XM_012789896.2 → XP_012645350.1  lathosterol oxidase

    See identical proteins and their annotated locations for XP_012645350.1

    UniProtKB/TrEMBL
    A0A8C5V0C5, A0A8C5W3V3
    Related
    ENSMICP00000036557.2, ENSMICT00000030995.2
    Conserved Domains (2) summary
    COG3000
    Location:41 → 257
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:123 → 253
    FA_hydroxylase; Fatty acid hydroxylase superfamily
Nucleotide Protein
Heading Accession and Version

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