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NGLY1 N-glycanase 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105883217, updated on 13-Mar-2024

Summary

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Gene symbol
NGLY1
Gene description
N-glycanase 1
See related
Ensembl:ENSMICG00000049359
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See NGLY1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 1 NC_033660.1 (17974655..18027619, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195431.1 (1225875..1278792, complement)

Chromosome 1 - NC_033660.1Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor beta Neighboring gene DNA topoisomerase II beta Neighboring gene heat shock cognate 71 kDa protein pseudogene Neighboring gene ras GTPase-activating protein-binding protein 1 pseudogene Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deglycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033660.1 Reference Mmur_3.0 Primary Assembly

    Range
    17974655..18027619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012786253.2 → XP_012641707.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X1

    UniProtKB/TrEMBL
    A0A8C5YF88
    Related
    ENSMICP00000050922.1, ENSMICT00000073377.1
    Conserved Domains (5) summary
    cd10459
    Location:17 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    COG1305
    Location:293 → 354
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam01841
    Location:278 → 354
    Transglut_core; Transglutaminase-like superfamily
    pfam03835
    Location:338 → 422
    Rad4; Rad4 transglutaminase-like domain
    pfam04721
    Location:457 → 651
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  2. XM_012786261.2 → XP_012641715.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X2

    UniProtKB/TrEMBL
    A0A8B7HUG5
    Conserved Domains (3) summary
    cd10459
    Location:17 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:278 → 334
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:440 → 634
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  3. XM_012786263.2 → XP_012641717.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X3

    UniProtKB/TrEMBL
    A0A8C5YI42
    Related
    ENSMICP00000051178.1, ENSMICT00000072707.1
    Conserved Domains (5) summary
    cd10459
    Location:17 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    COG1305
    Location:293 → 354
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam01841
    Location:278 → 354
    Transglut_core; Transglutaminase-like superfamily
    pfam03835
    Location:338 → 422
    Rad4; Rad4 transglutaminase-like domain
    cl10509
    Location:457 → 538
    PAW; PNGase C-terminal domain, mannose-binding module PAW
Nucleotide Protein
Heading Accession and Version

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