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SPHK1 sphingosine kinase 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105878971, updated on 13-Mar-2024

Summary

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Gene symbol
SPHK1
Gene description
sphingosine kinase 1
See related
Ensembl:ENSMICG00000013341
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See SPHK1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 16 NC_033675.1 (5855813..5859567, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012197131.1 (2377613..2381192)

Chromosome 16 - NC_033675.1Genomic Context describing neighboring genes Neighboring gene rhomboid 5 homolog 2 Neighboring gene aralkylamine N-acetyltransferase Neighboring gene ubiquitin conjugating enzyme E2 O Neighboring gene fatty acid-binding protein, heart-like Neighboring gene 40S ribosomal protein S11-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-erythro-sphingosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingosine kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033675.1 Reference Mmur_3.0 Primary Assembly

    Range
    5855813..5859567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012778886.2 → XP_012634340.1  sphingosine kinase 1 isoform X2

    See identical proteins and their annotated locations for XP_012634340.1

    UniProtKB/TrEMBL
    A0A8B7HBY5, A0A8C5V4L6
    Conserved Domains (2) summary
    PLN02958
    Location:11 → 345
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
    pfam00781
    Location:16 → 121
    DAGK_cat; Diacylglycerol kinase catalytic domain

  2. XM_012778884.2 → XP_012634338.1  sphingosine kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8B7HBZ1, A0A8C5V4L6
    Related
    ENSMICP00000012169.3, ENSMICT00000013345.3
    Conserved Domains (2) summary
    PLN02958
    Location:97 → 431
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
    pfam00781
    Location:102 → 207
    DAGK_cat; Diacylglycerol kinase catalytic domain

  3. XM_012778885.2 → XP_012634339.1  sphingosine kinase 1 isoform X2

    See identical proteins and their annotated locations for XP_012634339.1

    UniProtKB/TrEMBL
    A0A8B7HBY5, A0A8C5V4L6
    Conserved Domains (2) summary
    PLN02958
    Location:11 → 345
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
    pfam00781
    Location:16 → 121
    DAGK_cat; Diacylglycerol kinase catalytic domain

  4. XM_012778887.2 → XP_012634341.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8B7HBZ3
    Conserved Domains (1) summary
    pfam00781
    Location:102 → 207
    DAGK_cat; Diacylglycerol kinase catalytic domain
Nucleotide Protein
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