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PI4KA phosphatidylinositol 4-kinase alpha [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105877780, updated on 13-Mar-2024

Summary

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Gene symbol
PI4KA
Gene description
phosphatidylinositol 4-kinase alpha
See related
Ensembl:ENSMICG00000011230
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: Un
Exon count:
56
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) Unplaced Scaffold NW_017968521.1 (769053..888821, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012196931.1 (1839260..1959009)

NW_017968521.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105877784 Neighboring gene transmembrane protein 191C Neighboring gene serpin family D member 1 Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 pseudogene Neighboring gene polypeptide N-acetylgalactosaminyltransferase 1 pseudogene Neighboring gene synaptosome associated protein 29 Neighboring gene high mobility group protein B1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NW_017968521.1 Reference Mmur_3.0 Primary Assembly

    Range
    769053..888821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012776680.2 → XP_012632134.1  phosphatidylinositol 4-kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A8B7H6N4, A0A8C5W1F9
    Related
    ENSMICP00000034732.1, ENSMICT00000043071.2
    Conserved Domains (2) summary
    cd00871
    Location:1555 → 1730
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1791 → 2109
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  2. XM_012776681.2 → XP_012632135.1  phosphatidylinositol 4-kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A8B7H6Q0, A0A8C5XDH8
    Related
    ENSMICP00000010271.2, ENSMICT00000011278.3
    Conserved Domains (2) summary
    cd00871
    Location:1489 → 1664
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1725 → 2043
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha
Nucleotide Protein
Heading Accession and Version

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