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DEGS1 delta 4-desaturase, sphingolipid 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105863773, updated on 13-Mar-2024

Summary

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Gene symbol
DEGS1
Gene description
delta 4-desaturase, sphingolipid 1
See related
Ensembl:ENSMICG00000041977
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See DEGS1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 17 NC_033676.1 (37385472..37393032)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012202130.1 (7187353..7194911, complement)

Chromosome 17 - NC_033676.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105863777 Neighboring gene F-box protein 28 Neighboring gene E3 ubiquitin-protein ligase RING2 pseudogene Neighboring gene large proline-rich protein BAG6-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase DES1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033676.1 Reference Mmur_3.0 Primary Assembly

    Range
    37385472..37393032
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012751240.1 → XP_012606694.1  sphingolipid delta(4)-desaturase DES1 isoform X1

    UniProtKB/TrEMBL
    A0A8B7FER8
    Related
    ENSMICP00000049424.1, ENSMICT00000069009.1
    Conserved Domains (3) summary
    PLN02579
    Location:5 → 319
    PLN02579; sphingolipid delta-4 desaturase
    cd03508
    Location:26 → 315
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 40
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)

  2. XM_020281330.1 → XP_020136919.1  sphingolipid delta(4)-desaturase DES1 isoform X2

    UniProtKB/TrEMBL
    A0A8B7WNP5
    Conserved Domains (1) summary
    cd03508
    Location:1 → 279
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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