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DBT dihydrolipoamide branched chain transacylase E2 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105862370, updated on 13-Mar-2024

Summary

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Gene symbol
DBT
Gene description
dihydrolipoamide branched chain transacylase E2
See related
Ensembl:ENSMICG00000006218
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 2 NC_033661.1 (96947121..96988574, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012201508.1 (985203..1026646, complement)

Chromosome 2 - NC_033661.1Genomic Context describing neighboring genes Neighboring gene U6 snRNA-associated Sm-like protein LSm5 pseudogene Neighboring gene tRNA methyltransferase 13 homolog Neighboring gene leucine rich repeat containing 39 Neighboring gene transforming protein RhoA pseudogene Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene 28 kDa heat- and acid-stable phosphoprotein pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipoic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033661.1 Reference Mmur_3.0 Primary Assembly

    Range
    96947121..96988574 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012748604.1 → XP_012604058.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    A0A8C5VBZ9
    Related
    ENSMICP00000019517.1, ENSMICT00000029576.2
    Conserved Domains (4) summary
    cd06849
    Location:65 → 138
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:67 → 482
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:267 → 479
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:172 → 205
    E3_binding; e3 binding domain
Nucleotide Protein
Heading Accession and Version

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