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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105862245, updated on 13-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
See related
Ensembl:ENSMICG00000003427
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
18
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) X NC_033692.1 (144297888..144375233, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012201397.1 (1339103..1407106)

Chromosome X - NC_033692.1Genomic Context describing neighboring genes Neighboring gene RING finger and transmembrane domain-containing protein 1-like Neighboring gene melanoma-associated antigen D2-like Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033692.1 Reference Mmur_3.0 Primary Assembly

    Range
    144297888..144375233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020285160.1 → XP_020140749.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8B7X093, A0A8C6EG03
    Conserved Domains (2) summary
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  2. XM_020285162.1 → XP_020140751.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A8B7WZ82, A0A8C5UNK6
    Conserved Domains (2) summary
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:254 → 386
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  3. XM_020285157.1 → XP_020140746.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C5UNK6, A0A8C5Y6R7
    Related
    ENSMICP00000047112.1, ENSMICT00000063195.1
    Conserved Domains (2) summary
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:254 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  4. XM_020285159.1 → XP_020140748.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8B7X093, A0A8C6EG03
    Related
    ENSMICP00000040848.1, ENSMICT00000060074.1
    Conserved Domains (2) summary
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  5. XM_020285161.1 → XP_020140750.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8B7X093, A0A8C6EG03
    Conserved Domains (2) summary
    pfam01591
    Location:1 → 208
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:211 → 392
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  6. XM_020285158.1 → XP_020140747.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8B7WZ79, A0A8C5UNK6
    Conserved Domains (2) summary
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:254 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
Nucleotide Protein
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