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PLCB1 phospholipase C beta 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105861219, updated on 13-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
Ensembl:ENSMICG00000006563
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
32
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 18 NC_033677.1 (26973077..27734023)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012200934.1 (111848..254103)

Chromosome 18 - NC_033677.1Genomic Context describing neighboring genes Neighboring gene hydroxyacid oxidase 1 Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene rRNA 2'-O-methyltransferase fibrillarin-like Neighboring gene phospholipase C beta 4 Neighboring gene lysosomal associated membrane protein family member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033677.1 Reference Mmur_3.0 Primary Assembly

    Range
    26973077..27734023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020281914.1 → XP_020137503.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

    UniProtKB/TrEMBL
    A0A8B7WQF6, A0A8C5Y482
    Related
    ENSMICP00000045569.1, ENSMICT00000066877.1
    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:903 → 939
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1003 → 1176
    PLC-beta_C; PLC-beta C terminal
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
Nucleotide Protein
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