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HAGH hydroxyacylglutathione hydrolase [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105859606, updated on 13-Mar-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
See related
Ensembl:ENSMICG00000002132
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: 17
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 17 NC_033676.1 (1780121..1792996, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012200463.1 (703712..716577, complement)

Chromosome 17 - NC_033676.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene 60S ribosomal protein L27a-like Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene meiosis specific with OB-fold Neighboring gene 60S ribosomal protein L15-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033676.1 Reference Mmur_3.0 Primary Assembly

    Range
    1780121..1792996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012743540.2 → XP_012598994.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8B7EUT8
    Related
    ENSMICP00000043634.1, ENSMICT00000064650.1
    Conserved Domains (3) summary
    PLN02469
    Location:50 → 305
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:223 → 303
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:55 → 222
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  2. XM_012743541.2 → XP_012598995.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_012598995.1

    UniProtKB/TrEMBL
    A0A8B7EUT4
    Conserved Domains (3) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:174 → 254
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:6 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  3. XM_012743542.2 → XP_012598996.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_012598996.1

    UniProtKB/TrEMBL
    A0A8B7EUT4
    Related
    ENSMICP00000033545.1, ENSMICT00000031963.2
    Conserved Domains (3) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:174 → 254
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:6 → 173
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  4. XM_012743543.2 → XP_012598997.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C5UM52
    Related
    ENSMICP00000001952.3, ENSMICT00000002132.3
    Conserved Domains (1) summary
    cd07723
    Location:55 → 140
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
Nucleotide Protein
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