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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105826764, updated on 13-Mar-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSPCOG00000013478
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See HMGCS1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012155396.1 (1104126..1126756, complement)

NW_012155396.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 131 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene C-C motif chemokine ligand 28 Neighboring gene transmembrane protein 267

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012155396.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012155396.1 Reference Pcoq_1.0 Primary Assembly

    Range
    1104126..1126756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012664794.1 → XP_012520248.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_012520248.1

    UniProtKB/TrEMBL
    A0A2K6EU48
    Related
    ENSPCOP00000005250.1, ENSPCOT00000015610.1
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_012664793.1 → XP_012520247.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

    See identical proteins and their annotated locations for XP_012520247.1

    UniProtKB/TrEMBL
    A0A2K6EU48
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 469
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 469
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
Nucleotide Protein
Heading Accession and Version

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