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TLR4 toll like receptor 4 [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105826455, updated on 13-Mar-2024

Summary

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Gene symbol
TLR4
Gene description
toll like receptor 4
See related
Ensembl:ENSPCOG00000026664
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See TLR4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012155173.1 (6350334..6370935, complement)

NW_012155173.1Genomic Context describing neighboring genes Neighboring gene BMP/retinoic acid inducible neural specific 1 Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene ribosome biogenesis protein NSA2 homolog pseudogene Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene astrotactin 2 Neighboring gene tripartite motif containing 32

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012155173.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lipopolysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipopolysaccharide immune receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012155173.1 Reference Pcoq_1.0 Primary Assembly

    Range
    6350334..6370935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012664443.1 → XP_012519897.1  toll-like receptor 4

    UniProtKB/TrEMBL
    A0A2K6GPK2
    Related
    ENSPCOP00000028147.1, ENSPCOT00000039028.1
    Conserved Domains (5) summary
    smart00255
    Location:673 → 815
    TIR; Toll - interleukin 1 - resistance
    cd00116
    Location:370 → 580
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:374 → 399
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:54 → 114
    LRR_8; Leucine rich repeat
    cl15307
    Location:578 → 622
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
Nucleotide Protein
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