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LTA4H leukotriene A4 hydrolase [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105826106, updated on 13-Mar-2024

Summary

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Gene symbol
LTA4H
Gene description
leukotriene A4 hydrolase
See related
Ensembl:ENSPCOG00000016371
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See LTA4H in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012154729.1 (4471593..4499998)

NW_012154729.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 17 Neighboring gene ETS transcription factor ELK3 Neighboring gene 39S ribosomal protein L35, mitochondrial pseudogene Neighboring gene histidine ammonia-lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012154729.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epoxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables leukotriene-A4 hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leukotriene A-4 hydrolase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012154729.1 Reference Pcoq_1.0 Primary Assembly

    Range
    4471593..4499998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012664015.1 → XP_012519469.1  leukotriene A-4 hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A2K6F7L9, A0A2K6F7N8
    Related
    ENSPCOP00000009976.1, ENSPCOT00000020550.1
    Conserved Domains (3) summary
    cd09599
    Location:6 → 450
    M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
    TIGR02411
    Location:6 → 608
    leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
    pfam09127
    Location:468 → 607
    Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal

  2. XM_012664016.1 → XP_012519470.1  leukotriene A-4 hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A2K6F7K7
    Related
    ENSPCOP00000009982.1, ENSPCOT00000020556.1
    Conserved Domains (3) summary
    cd09599
    Location:6 → 450
    M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
    pfam01433
    Location:21 → 387
    Peptidase_M1; Peptidase family M1
    pfam09127
    Location:468 → 520
    Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
Nucleotide Protein
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