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PKLR pyruvate kinase L/R [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105821897, updated on 13-Mar-2024

Summary

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Gene symbol
PKLR
Gene description
pyruvate kinase L/R
See related
Ensembl:ENSPCOG00000028225
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See PKLR in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012151840.1 (2572135..2581122)

NW_012151840.1Genomic Context describing neighboring genes Neighboring gene RUN and SH3 domain containing 1 Neighboring gene RUSC1 antisense RNA 1 Neighboring gene farnesyl diphosphate synthase Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene CDC like kinase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012151840.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKLR
Names
pyruvate kinase, liver and RBC

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012151840.1 Reference Pcoq_1.0 Primary Assembly

    Range
    2572135..2581122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012658733.1 → XP_012514187.1  pyruvate kinase PKLR

    UniProtKB/TrEMBL
    A0A2K6GXG5
    Related
    ENSPCOP00000030933.1, ENSPCOT00000041886.1
    Conserved Domains (2) summary
    cd00288
    Location:83 → 571
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:84 → 568
    pyruv_kin; pyruvate kinase
Nucleotide Protein
Heading Accession and Version

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