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TLR8 toll like receptor 8 [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105820965, updated on 13-Mar-2024

Summary

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Gene symbol
TLR8
Gene description
toll like receptor 8
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See TLR8 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012151374.1 (1468804..1479220)

NW_012151374.1Genomic Context describing neighboring genes Neighboring gene phosphoribosyl pyrophosphate synthetase 2 Neighboring gene toll like receptor 7 Neighboring gene thymosin beta 4 X-linked

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012151374.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pattern recognition receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interleukin-6 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: toll-like receptor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012151374.1 Reference Pcoq_1.0 Primary Assembly

    Range
    1468804..1479220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012657566.1 → XP_012513020.1  LOW QUALITY PROTEIN: toll-like receptor 8

    UniProtKB/TrEMBL
    A0A2K6FN88
    Conserved Domains (5) summary
    smart00255
    Location:876 → 1012
    TIR; Toll - interleukin 1 - resistance
    cd00116
    Location:63 → 255
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:62 → 85
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:686 → 745
    LRR_8; Leucine rich repeat
    cl15307
    Location:768 → 813
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
Nucleotide Protein
Heading Accession and Version

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