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ALOX12 arachidonate 12-lipoxygenase, 12S type [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105819472, updated on 13-Mar-2024

Summary

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Gene symbol
ALOX12
Gene description
arachidonate 12-lipoxygenase, 12S type
See related
Ensembl:ENSPCOG00000026242
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See ALOX12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012150641.1 (2474760..2486797, complement)

NW_012150641.1Genomic Context describing neighboring genes Neighboring gene BCL6B transcription repressor Neighboring gene uncharacterized LOC105819471 Neighboring gene BPTF associated chromatin complex component 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012150641.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12S-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012150641.1 Reference Pcoq_1.0 Primary Assembly

    Range
    2474760..2486797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012655725.1 → XP_012511179.1  arachidonate 12-lipoxygenase, 12S-type

    UniProtKB/TrEMBL
    A0A2K6GML9
    Related
    ENSPCOP00000027488.1, ENSPCOT00000038311.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:221 → 654
    Lipoxygenase; Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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