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HAGH hydroxyacylglutathione hydrolase [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105813151, updated on 13-Mar-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
See related
Ensembl:ENSPCOG00000026794
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012148285.1 (700573..713409, complement)

NW_012148285.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene 60S ribosomal protein L27a pseudogene Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene obg-like ATPase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012148285.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012148285.1 Reference Pcoq_1.0 Primary Assembly

    Range
    700573..713409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012647777.1 → XP_012503231.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A2K6GQ68
    Related
    ENSPCOP00000028359.1, ENSPCOT00000039255.1
    Conserved Domains (3) summary
    PLN02469
    Location:50 → 305
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:223 → 303
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:55 → 222
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

  2. XM_012647778.1 → XP_012503232.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2K6GQ67
    Related
    ENSPCOP00000028362.1, ENSPCOT00000039258.1
    Conserved Domains (1) summary
    cd07723
    Location:55 → 145
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
Nucleotide Protein
Heading Accession and Version

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