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ERV3-1 endogenous retrovirus group 3 member 1, envelope [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105600138, updated on 13-Mar-2024

Summary

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Gene symbol
ERV3-1
Gene description
endogenous retrovirus group 3 member 1, envelope
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Summary
Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of an endogenous retrovirus provirus that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene is expressed at a higher level in the adrenal cortex and placenta and may play a role in human physiology and disease. [provided by RefSeq, Jul 2015]
Orthologs
human all
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Genomic context

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See ERV3-1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012002557.1 (762988..801829, complement)

NW_012002557.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 273 Neighboring gene zinc finger protein 85-like Neighboring gene probable ribosome biogenesis protein RLP24 pseudogene Neighboring gene zinc finger protein 92

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012002557.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation and loss of the ERV3 open reading frame in primates. Hervé CA, et al. Genomics, 2004 May. PMID 15081124
  2. A revised nomenclature for transcribed human endogenous retroviral loci. Mayer J, et al. Mob DNA, 2011 May 4. PMID 21542922, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
endogenous retrovirus group 3 member 1 Env polyprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308247.1 → NP_001295176.1  endogenous retrovirus group 3 member 1 Env polyprotein precursor

    See identical proteins and their annotated locations for NP_001295176.1

    Status: REVIEWED

    Source sequence(s)
    JZLG01034977
    Conserved Domains (1) summary
    cd09850
    Location:521 → 597
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains

RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012002557.1 Reference Caty_1.0

    Range
    762988..801829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012091004.1 → XP_011946394.1  endogenous retrovirus group 3 member 1 Env polyprotein

    See identical proteins and their annotated locations for XP_011946394.1

    Conserved Domains (1) summary
    cd09850
    Location:521 → 597
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains

  2. XM_012091001.1 → XP_011946391.1  endogenous retrovirus group 3 member 1 Env polyprotein

    Conserved Domains (1) summary
    cd09850
    Location:521 → 597
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains

  3. XM_012091003.1 → XP_011946393.1  endogenous retrovirus group 3 member 1 Env polyprotein

    See identical proteins and their annotated locations for XP_011946393.1

    Conserved Domains (1) summary
    cd09850
    Location:521 → 597
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains

  4. XM_012091002.1 → XP_011946392.1  endogenous retrovirus group 3 member 1 Env polyprotein

    See identical proteins and their annotated locations for XP_011946392.1

    Conserved Domains (1) summary
    cd09850
    Location:521 → 597
    Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains
Nucleotide Protein
Heading Accession and Version

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