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PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105592559, updated on 13-Mar-2024

Summary

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Gene symbol
PIK3C3
Gene description
phosphatidylinositol 3-kinase catalytic subunit type 3
See related
Ensembl:ENSCATG00000041912
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See PIK3C3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001406.1 (12755824..12885866, complement)

NW_012001406.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105592558 Neighboring gene uncharacterized LOC105592557 Neighboring gene UPF0235 protein C15orf40-like Neighboring gene uncharacterized LOC105592560

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001406.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase catalytic subunit type 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001406.1 Reference Caty_1.0

    Range
    12755824..12885866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012074707.1 → XP_011930097.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2

    UniProtKB/TrEMBL
    A0A2K5NLZ4, A0A2K5NLZ9
    Related
    ENSCATP00000038553.1, ENSCATT00000062859.1
    Conserved Domains (3) summary
    cd08397
    Location:24 → 123
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:220 → 440
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:476 → 820
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  2. XM_012074704.1 → XP_011930094.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

    UniProtKB/TrEMBL
    A0A2K5NLZ9, A0A2K5NME6
    Related
    ENSCATP00000038550.1, ENSCATT00000062856.1
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283 → 503
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:539 → 883
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
Nucleotide Protein
Heading Accession and Version

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