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PLS1 plastin 1 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105586341, updated on 13-Mar-2024

Summary

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Gene symbol
PLS1
Gene description
plastin 1
See related
Ensembl:ENSCATG00000034817
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See PLS1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012009911.1 (2474192..2587633, complement)

NW_012009911.1Genomic Context describing neighboring genes Neighboring gene procollagen C-endopeptidase enhancer 2 Neighboring gene transient receptor potential cation channel subfamily C member 1 Neighboring gene ATR serine/threonine kinase Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 1 pseudogene Neighboring gene 5'-3' exoribonuclease 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012009911.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin filament network formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in actin filament bundle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plastin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012009911.1 Reference Caty_1.0

    Range
    2474192..2587633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012061206.1 → XP_011916596.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916596.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  2. XM_012061208.1 → XP_011916598.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916598.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  3. XM_012061211.1 → XP_011916601.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916601.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  4. XM_012061209.1 → XP_011916599.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916599.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  5. XM_012061210.1 → XP_011916600.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916600.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  6. XM_012061205.1 → XP_011916595.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916595.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Related
    ENSCATP00000022376.1, ENSCATT00000046584.1
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  7. XM_012061212.1 → XP_011916602.1  plastin-1 isoform X1

    See identical proteins and their annotated locations for XP_011916602.1

    UniProtKB/TrEMBL
    A0A2K5MAY2
    Conserved Domains (3) summary
    COG5069
    Location:13 → 621
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd21323
    Location:100 → 244
    CH_PLS1_rpt1; first calponin homology (CH) domain found in plastin-1
    cd21329
    Location:391 → 508
    CH_PLS1_rpt3; third calponin homology (CH) domain found in plastin-1

  8. XM_012061213.1 → XP_011916603.1  plastin-1 isoform X2

    Conserved Domains (4) summary
    smart00033
    Location:399 → 502
    CH; Calponin homology domain
    cd00014
    Location:123 → 238
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00051
    Location:15 → 81
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:16 → 80
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
Heading Accession and Version

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